Post-harvest losses are a significant problem worldwide, leading to a waste of resources when they are becoming scarcer. Rather than putting more energy into increasing production volume, addressing post-harvest losses can increase food availability without increasing yields. Using maize in Ethiopia to introduce gendering post-harvest loss research, we analyze the gendered division of labor in post-harvest management and then discuss implications. Without gendering post-harvest loss research, it is possible that gender harms are enacted when women’s livelihoods are impacted in the process of reducing post-harvest losses, and this may compromise food security.